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human SFRS6 shRNA silencing Adenovirus

Name 
Ad-h-SFRS6-shRNA
Cat No 
shADV-222811
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SRSF6.

shADV-222811
Ad-h-SFRS6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SRSF6 (serine and arginine rich splicing factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B52; epididymis secretory protein Li 91; HEL-S-91; pre-mRNA-splicing factor SRP55; serine/arginine-rich splicing factor 6; SFRS6; Splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6; SRP55
Description (eCommerce)
Serine/arginine-rich protein 55 (SRp55) is encoded by the SRSF6 gene. SRp55 is involved in mRNA splicing and may play a role in the determination of alternative splicing. SRp55 belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12 [taken from NCBI Entrez Gene (Gene ID: 6431)].
Description (Vector)
SRSF6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.
Gene ID
6431
Gene Name (eCommerce)
serine and arginine rich splicing factor 6
Gene Name (Vector)
serine and arginine rich splicing factor 6
Gene Symbol
SRSF6
HGNC ID
HGNC:10788
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1035
Protein Name (eCommerce)
Serine/arginine-rich splicing factor 6
RefSeq ID
NM_006275
RefSeq Synonyms
NM_006275, BC006832,
Research Areas
Gene Expression,Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA Transport,RNA Binding,RNA Processing,RNA Transport,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,infectious_disease,cell_biology
Species
human
Target Sentence
Serine/arginine-rich protein 55 (SRp55) is encoded by the SRSF6 gene. SRp55 is involved in mRNA splicing and may play a role in the determination of alternative splicing. SRp55 belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12 [taken from NCBI Entrez Gene (Gene ID: 6431)].
UniGene ID
Hs.6891
UniProt ID (eCommerce)
Q13247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.