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human SERPINH1 shRNA silencing Adenovirus

Name 
Ad-h-SERPINH1-shRNA
Cat No 
shADV-222711
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SERPINH1.

shADV-222711
Ad-h-SERPINH1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SERPINH1 (serpin family H member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AsTP3; CBP1; CBP2; gp46; HSP47; OI10; PIG14; PPROM; RA-A47; SERPINH2
Description (Vector)
SERPINH1 encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Gene ID
871
Gene Name (Vector)
serpin family H member 1
Gene Symbol
SERPINH1
HGNC ID
HGNC:1546
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_001235
RefSeq Synonyms
NM_001235, NM_001207014, BC070087, BC036298, BC014623,
Species
human
UniGene ID
Hs.596449

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.