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human SEPX1 shRNA silencing Adenovirus

Name 
Ad-h-SEPX1-shRNA
Cat No 
shADV-222625
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MSRB1.

shADV-222625
Ad-h-SEPX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MSRB1 (methionine sulfoxide reductase B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSPC270; SELR; SELX; SepR; SEPX1
Description (Vector)
MSRB1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol.
Gene ID
51734
Gene Name (Vector)
methionine sulfoxide reductase B1
Gene Symbol
MSRB1
HGNC ID
HGNC:14133
ORF Size (aa)
351
RefSeq ID
NM_016332
RefSeq Synonyms
NM_016332, BC003127,
Species
human
UniGene ID
Hs.655346

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.