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human SEL1L shRNA silencing Adenovirus

Name 
Ad-h-SEL1L-shRNA
Cat No 
shADV-222515
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SEL1L.

shADV-222515
Ad-h-SEL1L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SEL1L (SEL1L ERAD E3 ligase adaptor subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PRO1063; SEL1-LIKE; SEL1L1
Description (Vector)
SEL1L is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6400
Gene Name (Vector)
SEL1L ERAD E3 ligase adaptor subunit
Gene Symbol
SEL1L
HGNC ID
HGNC:10717
ORF Size (aa)
2385
ORF Size (bp)
2385 bp
RefSeq ID
NM_005065
RefSeq Synonyms
NM_005065, NM_001244984, BC172577, BC172282,
Species
human
UniGene ID
Hs.181300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.