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human SEC31A shRNA silencing Adenovirus

Name 
Ad-h-SEC31A-shRNA
Cat No 
shADV-222498
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SEC31A.

shADV-222498
Ad-h-SEC31A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SEC31A (SEC31 homolog A, COPII coat complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ABP125; ABP130; HSPC275; HSPC334; protein transport protein Sec31A; SEC31 homolog A, COPII coating complex component; SEC31L1; SEC31-like protein 1; SEC31-related protein A; web1-like protein; yeast Sec31p homolog
Description (eCommerce)
Sec31A is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function [taken from NCBI GeneID:22872].
Description (Vector)
SEC31A is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
22872
Gene Name (eCommerce)
SEC31 homolog A, COPII coat complex component
Gene Name (Vector)
SEC31 homolog A, COPII coat complex component
Gene Symbol
SEC31A
HGNC ID
HGNC:17052
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3321
ORF Size (bp)
3321 bp
Protein Name (eCommerce)
Protein transport protein Sec31A
RefSeq ID
NM_014933
RefSeq Synonyms
NM_016211, NM_014933, NM_001318120, NM_001318119, NM_001300745, NM_001300744, NM_001191049, NM_001077208, NM_001077207, NM_001077206, BC143492, BC143491, BC143489, BC117221, BC084583, BC047883,
Research Areas
Antigen Processing and Presentation,Cancer,Golgi Apparatus,Immunology,Metabolism/Metabolic Process,Signal Transduction,Translational Control,Transport
Research Areas (Faceted)
cancer,cell_biology,immunology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Sec31A is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function [taken from NCBI GeneID:22872].
UniGene ID
Hs.370024
UniProt ID (eCommerce)
O94979

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.