human SEC13 shRNA silencing Adenovirus

Name 
Ad-h-SEC13-shRNA
Cat No 
shADV-222463
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SEC13.

shADV-222463
Ad-h-SEC13-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D3S1231E; GATOR complex protein SEC13; npp-20; protein SEC13 homolog; SEC13 homolog, nuclear pore and COPII coating complex component; SEC13L1; SEC13-like 1 isoform; SEC13-like protein 1; SEC13R; SEC13-related protein
Description (eCommerce)
Sec13 belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins [taken from NCBI Entrez Gene (Gene ID: 6396)].
Description (Vector)
SEC13 belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
Gene ID
6396
Gene Name (eCommerce)
SEC13 homolog, nuclear pore and COPII coat complex component
Gene Name (Vector)
SEC13 homolog, nuclear pore and COPII coat complex component
Gene Symbol
SEC13
HGNC ID
HGNC:10697
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
978
Protein Name (eCommerce)
Protein SEC13 homolog
RefSeq ID
NM_183352
RefSeq Synonyms
NM_183352, NM_030673, NM_001278946, NM_001136232, NM_001136026, BC091506, BC002634,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Golgi Apparatus,Immunology,Metabolism/Metabolic Process,mRNA transport,RNA Transport,Signal Transduction,Translational Control,Transport
Research Areas (Faceted)
signal_transduction,immunology,cell_biology,cell_cycle,immunology,metabolism,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Sec13 belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins [taken from NCBI Entrez Gene (Gene ID: 6396)].
UniGene ID
Hs.166924
UniProt ID (eCommerce)
P55735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.