human SDC2 shRNA silencing Adenovirus

Name 
Ad-h-SDC2-shRNA
Cat No 
shADV-222413
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human SDC2.

shADV-222413
Ad-h-SDC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SDC2 (syndecan 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD362; HSPG; HSPG1; SYND2
Description (Vector)
SDC2 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
Gene ID
6383
Gene Name (Vector)
syndecan 2
Gene Symbol
SDC2
HGNC ID
HGNC:10659
ORF Size (aa)
606
RefSeq ID
NM_002998
RefSeq Synonyms
NM_002998, BC049836, BC030133,
Species
human
UniGene ID
Hs.598247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.