human SCRIB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SCRIB.
shADV-222390
Ad-h-SCRIB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SCRIB (scribbled planar cell polarity protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CRIB1; SCRB1; SCRIB1; Vartul
Description (Vector)
SCRIB encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Gene ID
23513
Gene Name (Vector)
scribbled planar cell polarity protein
Gene Symbol
SCRIB
HGNC ID
HGNC:30377
ORF Size (aa)
4965
ORF Size (bp)
4965 bp
RefSeq ID
NM_015356
RefSeq Synonyms
NM_182706, NM_015356, BC146321,
Species
human
UniGene ID
Hs.436329
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.