human SCP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SCP2.
shADV-222387
Ad-h-SCP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SCP2 (sterol carrier protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NLTP; NSL-TP; SCP-2; SCP-CHI; SCP-X; SCPX
Description (Vector)
SCP2 encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Gene ID
6342
Gene Name (Vector)
sterol carrier protein 2
Gene Symbol
SCP2
HGNC ID
HGNC:10606
ORF Size (aa)
969
RefSeq ID
NM_002979
RefSeq Synonyms
NM_002979, NM_001330587, NM_001193617, NM_001193600, NM_001193599, NM_001007250, NM_001007100, NM_001007099, NM_001007098, BC067108,
Species
human
UniGene ID
Hs.709369
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.