human SCN5A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SCN5A.
shADV-222374
Ad-h-SCN5A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SCN5A (sodium voltage-gated channel alpha subunit 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1
Description (Vector)
SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.
Gene ID
6331
Gene Name (Vector)
sodium voltage-gated channel alpha subunit 5
Gene Symbol
SCN5A
HGNC ID
HGNC:10593
ORF Size (aa)
5952
ORF Size (bp)
5952 bp
RefSeq ID
NM_000335
RefSeq Synonyms
NM_198056, NM_001160161, NM_001160160, NM_001099405, NM_001099404, NM_000335, BC144621, BC140813,
Species
human
UniGene ID
Hs.517898
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.