human SCD shRNA silencing Adenovirus

Name 
Ad-h-SCD-shRNA
Cat No 
shADV-222321
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SCD.

shADV-222321
Ad-h-SCD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SCD (stearoyl-CoA desaturase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
acyl-CoA desaturase; delta(9)-desaturase; Delta-9 desaturase; FADS5; fatty acid desaturase; hSCD1; MSTP008; predicted protein of HQ0998; SCD1; SCDOS; Stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase opposite strand
Description (eCommerce)
Stearoyl-CoA desaturase (SCD) is an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. SCD belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum [taken from NCBI Entrez Gene (Gene ID: 6319)].
Description (Vector)
SCD encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17.
Gene ID
6319
Gene Name (eCommerce)
stearoyl-CoA desaturase
Gene Name (Vector)
stearoyl-CoA desaturase
Gene Symbol
SCD
HGNC ID
HGNC:10571
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
Protein Name (eCommerce)
Acyl-CoA desaturase
RefSeq ID
NM_005063
RefSeq Synonyms
NM_005063, BC062303,
Research Areas
Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Stearoyl-CoA desaturase (SCD) is an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. SCD belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum [taken from NCBI Entrez Gene (Gene ID: 6319)].
UniGene ID
Hs.597496
UniProt ID (eCommerce)
O00767

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.