human SAT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SAT1.
shADV-222268
Ad-h-SAT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SAT1 (spermidine/spermine N1-acetyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
Description (Vector)
SAT1 belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
Gene ID
6303
Gene Name (Vector)
spermidine/spermine N1-acetyltransferase 1
Gene Symbol
SAT1
HGNC ID
HGNC:10540
ORF Size (aa)
516
RefSeq ID
NM_002970
RefSeq Synonyms
NM_002970, BC008424, BC002503,
Species
human
UniGene ID
Hs.28491
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.