human RTN2 shRNA silencing Adenovirus

Name 
Ad-h-RTN2-shRNA
Cat No 
shADV-222088
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RTN2.

shADV-222088
Ad-h-RTN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RTN2 (reticulon 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NSP2; NSPL1; NSPLI; SPG12
Description (Vector)
RTN2 belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12.
Gene ID
6253
Gene Name (Vector)
reticulon 2
Gene Symbol
RTN2
HGNC ID
HGNC:10468
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
RefSeq ID
NM_005619
RefSeq Synonyms
NM_206901, NM_206900, NM_005619, BC073874, BC014244,
Species
human
UniGene ID
Hs.47517

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.