human RSPH4A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RSPH4A.
shADV-222061
Ad-h-RSPH4A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RSPH4A (radial spoke head 4 homolog A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CILD11; dJ412I7.1; RSHL3; RSPH6B
Description (Vector)
RSPH4A encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.
Gene ID
345895
Gene Name (Vector)
radial spoke head 4 homolog A
Gene Symbol
RSPH4A
HGNC ID
HGNC:21558
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
RefSeq ID
NM_001010892
RefSeq Synonyms
NM_001161664, NM_001010892, BC106949,
Species
human
UniGene ID
Hs.160380
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.