human RPL21 shRNA silencing Adenovirus

Name 
Ad-h-RPL21-shRNA
Cat No 
shADV-221622
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RPL21.

shADV-221622
Ad-h-RPL21-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPL21 (ribosomal protein L21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
54
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60S ribosomal protein L21; HYPT12; L21; large ribosomal subunit protein eL21
Description (eCommerce)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL21/Ribosomal Protein L21 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6144)].
Description (Vector)
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Gene ID
6144
Gene Name (eCommerce)
ribosomal protein L21
Gene Name (Vector)
ribosomal protein L21
Gene Symbol
RPL21
HGNC ID
HGNC:10313
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
483
Protein Name (eCommerce)
60S ribosomal protein L21
RefSeq ID
NM_000982
RefSeq Synonyms
NM_000982, BC104667, BC071902, BC070330, BC070323, BC070184, BC062981, BC007505, BC001603,
Research Areas
Gene Expression,Host-Virus Interactions,Metabolism/Metabolic Process,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,metabolism,transcription_translation
Species
human
Target Sentence
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL21/Ribosomal Protein L21 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm [taken from NCBI Entrez Gene (Gene ID: 6144)].
UniGene ID
Hs.535873
UniProt ID (eCommerce)
P46778

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.