human RORA shRNA silencing Adenovirus

Name 
Ad-h-RORA-shRNA
Cat No 
shADV-221492
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RORA.

shADV-221492
Ad-h-RORA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RORA (RAR related orphan receptor A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA
Description (Vector)
RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Gene ID
6095
Gene Name (Vector)
RAR related orphan receptor A
Gene Symbol
RORA
HGNC ID
HGNC:10258
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_002943
RefSeq Synonyms
NM_134262, NM_134261, NM_134260, NM_002943, BC100990, BC100989, BC100988, BC100987, BC008831,
Species
human
UniGene ID
Hs.655155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.