human RLN3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RLN3.
shADV-221277
Ad-h-RLN3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RLN3 (relaxin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H3; insl7; RXN3; ZINS4
Description (Vector)
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes.
Gene ID
117579
Gene Name (Vector)
relaxin 3
Gene Symbol
RLN3
HGNC ID
HGNC:17135
ORF Size (aa)
429
RefSeq ID
NM_080864
RefSeq Synonyms
NM_080864, NM_001311197, BC140935,
Species
human
UniGene ID
Hs.352155
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.