human RHOU shRNA silencing Adenovirus

Name
Ad-h-RHOU-shRNA

Cat No
shADV-221198

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RHOU.

shADV-221198

Ad-h-RHOU-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RHOU (ras homolog family member U). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ARHU; CDC42L1; G28K; hG28K; WRCH1

Description (Vector)

RHOU encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.

Gene ID

58480

Gene Name (Vector)

ras homolog family member U

Gene Symbol

RHOU

HGNC ID

HGNC:17794

ORF Size (aa)

777

RefSeq ID

NM_021205

RefSeq Synonyms

NM_021205, BC040076,

Species

human

UniGene ID

Hs.647774

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.