human RHOQ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RHOQ.
shADV-221188
Ad-h-RHOQ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RHOQ (ras homolog family member Q). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHQ; HEL-S-42; RASL7A; TC10; TC10A
Description (Vector)
RHOQ encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
Gene ID
23433
Gene Name (Vector)
ras homolog family member Q
Gene Symbol
RHOQ
HGNC ID
HGNC:17736
ORF Size (aa)
618
RefSeq ID
NM_012249
RefSeq Synonyms
NM_012249, BC101806, BC093805, BC070485, BC065291, BC056154,
Species
human
UniGene ID
Hs.709193
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.