human RGS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RGS1.
shADV-221106
Ad-h-RGS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RGS1 (regulator of G-protein signaling 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1R20; BL34; HEL-S-87; IER1; IR20
Description (Vector)
RGS1 encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Gene ID
5996
Gene Name (Vector)
regulator of G-protein signaling 1
Gene Symbol
RGS1
HGNC ID
HGNC:9991
ORF Size (aa)
591
RefSeq ID
NM_002922
RefSeq Synonyms
NM_002922, BC015510,
Species
human
UniGene ID
Hs.75256
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.