human RFX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RFX1.
shADV-221066
Ad-h-RFX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RFX1 (regulatory factor X1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EFC; EF-C; enhancer factor C; MHC class II regulatory factor RFX; MHC class II regulatory factor RFX1; Regulatory factor X 1; regulatory factor X, 1 (influences HLA class II expression); RFX; trans-acting regulatory factor 1; transcription factor RFX1
Description (eCommerce)
Regulatory factor X, 1 (RFX1) is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression [taken from NCBI Entrez Gene (Gene ID: 5989)].
Description (Vector)
RFX1 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.
Gene ID
5989
Gene Name (eCommerce)
regulatory factor X1
Gene Name (Vector)
regulatory factor X1
Gene Symbol
RFX1
HGNC ID
HGNC:9982
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2940
ORF Size (bp)
2940 bp
Protein Name (eCommerce)
MHC class II regulatory factor RFX1
RefSeq ID
NM_002918
RefSeq Synonyms
NM_002918, BC049826,
Research Areas
Immunology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,transcription_translation
Species
human
Target Sentence
Regulatory factor X, 1 (RFX1) is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression [taken from NCBI Entrez Gene (Gene ID: 5989)].
UniGene ID
Hs.655215
UniProt ID (eCommerce)
P22670
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.