human RELB shRNA silencing Adenovirus

Name 
Ad-h-RELB-shRNA
Cat No 
shADV-220996
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RELB.

shADV-220996
Ad-h-RELB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RELB (RELB proto-oncogene, NF-kB subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IMD53; IREL; I-REL; REL-B; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Description (eCommerce)
The members of the Rel family bear a characteristic 300 amino acid N-terminal Rel homology domain (RHD). The Rel members include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The Rel proteins combine as heterodimers or homodimers to form the NF-kappa B transcription factor which functions to mediate pleiotropic cellular effects in response to injury, infection and stress.
Gene ID
5971
Gene Name (eCommerce)
RELB proto-oncogene, NF-kB subunit
Gene Name (Vector)
RELB proto-oncogene, NF-kB subunit
Gene Symbol
RELB
HGNC ID
HGNC:9956
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1740
ORF Size (bp)
1740 bp
Protein Name (eCommerce)
Transcription factor RelB
RefSeq ID
NM_006509
RefSeq Synonyms
NM_006509, BC028013,
Research Areas
Antigen Processing and Presentation,Cytoskeleton,DNA Damage/Repair,Gene Expression,Host-Virus Interactions,Immunology,Interleukin Signaling,MAPK Signaling,NF-kB Signaling,RANKL-RANK Signaling,Signal Transduction,TNF Signaling,Transcription Factor/Regulator,TSLP Signaling,TWEAK Signaling
Research Areas (Faceted)
signal_transduction,immunology,cell_biology,genetics,transcription_translation,infectious_disease,immunology,signal_transduction,genetics,transcription_translation,signal_transduction
Species
human
Target Sentence
The members of the Rel family bear a characteristic 300 amino acid N-terminal Rel homology domain (RHD). The Rel members include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The Rel proteins combine as heterodimers or homodimers to form the NF-kappa B transcription factor which functions to mediate pleiotropic cellular effects in response to injury, infection and stress.
UniGene ID
Hs.654402
UniProt ID (eCommerce)
Q01201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.