human RD3 shRNA silencing Adenovirus

Name 
Ad-h-RD3-shRNA
Cat No 
shADV-220955
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RD3.

shADV-220955
Ad-h-RD3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RD3 (retinal degeneration 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C1orf36; LCA12
Description (Vector)
RD3 encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants.
Gene ID
343035
Gene Name (Vector)
retinal degeneration 3
Gene Symbol
RD3
HGNC ID
HGNC:19689
ORF Size (aa)
588
RefSeq ID
NM_183059
RefSeq Synonyms
NM_183059, NM_001164688, BC065541,
Species
human
UniGene ID
Hs.632495

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.