human LRRFIP1 Over-expression AAV

Name
AAV-h-LRRFIP1

Cat No
AAV-214599

Availability
4-5 weeks

This is an AAV expressing Human LRRFIP1.

AAV-214599

AAV-h-LRRFIP1

Ready-to-use AAV expressing Human LRRFIP1 (LRR binding FLII interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FLAP1; FLAP-1; FLIIAP1; GC-binding factor 2; GCF2; GCF-2; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP

Description (eCommerce)

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP1 may control smooth muscle cell proliferation following artery injury through PDGFA repression. LRRFIP1 May also bind double-stranded RNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q32MZ4].

Gene ID

9208

Gene Name (eCommerce)

LRR binding FLII interacting protein 1

Gene Name (Vector)

LRR binding FLII interacting protein 1

Gene Symbol

LRRFIP1

HGNC ID

HGNC:6702

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2259

ORF Size (bp)

2259 bp

Protein Name (eCommerce)

Leucine-rich repeat flightless-interacting protein 1

RefSeq ID

NM_004735

RefSeq Synonyms

NM_004735, NM_001137553, NM_001137552, NM_001137551, NM_001137550, BC108914, BC108913, BC010662,

Research Areas

Cytoskeleton,FGF Signaling,Immunology,Innate Immunity,RNA Binding,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP1 may control smooth muscle cell proliferation following artery injury through PDGFA repression. LRRFIP1 May also bind double-stranded RNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q32MZ4].

UniGene ID

Hs.471779

UniProt ID (eCommerce)

Q32MZ4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.