human RAB1A shRNA silencing Adenovirus

Name 
Ad-h-RAB1A-shRNA
Cat No 
shADV-220507
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RAB1A.

shADV-220507
Ad-h-RAB1A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAB1A (RAB1A, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GTP binding protein Rab1a; Rab GTPase YPT1 homolog; RAB1; RAB1, member RAS oncogene family; ras-related protein Rab-1A; YPT1; YPT1-related protein
Description (eCommerce)
RAB1A is a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus [taken from NCBI Entrez Gene (Gene ID: 5861)].
Description (Vector)
RAB1A encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.
Gene ID
5861
Gene Name (eCommerce)
RAB1A, member RAS oncogene family
Gene Name (Vector)
RAB1A, member RAS oncogene family
Gene Symbol
RAB1A
HGNC ID
HGNC:9758
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
618
Protein Name (eCommerce)
Ras-related protein Rab-1A
RefSeq ID
NM_004161
RefSeq Synonyms
NM_015543, NM_004161, BC000905,
Research Areas
Autophagy,Cell Cycle,Golgi Apparatus,PLK1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
RAB1A is a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus [taken from NCBI Entrez Gene (Gene ID: 5861)].
UniGene ID
Hs.310645
UniProt ID (eCommerce)
P62820

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.