human QDPR shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human QDPR.
shADV-220465
Ad-h-QDPR-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human QDPR (quinoid dihydropteridine reductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHPR; PKU2; SDR33C1
Description (Vector)
QDPR encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Gene ID
5860
Gene Name (Vector)
quinoid dihydropteridine reductase
Gene Symbol
QDPR
HGNC ID
HGNC:9752
ORF Size (aa)
735
RefSeq ID
NM_000320
RefSeq Synonyms
NM_001306140, NM_000320, BC000576,
Species
human
UniGene ID
Hs.75438
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.