human PYGM shRNA silencing Adenovirus

Name 
Ad-h-PYGM-shRNA
Cat No 
shADV-220451
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human PYGM.

shADV-220451
Ad-h-PYGM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PYGM (glycogen phosphorylase, muscle associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
PYGM encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.
Gene ID
5837
Gene Name (Vector)
glycogen phosphorylase, muscle associated
Gene Symbol
PYGM
HGNC ID
HGNC:9726
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_005609
RefSeq Synonyms
NM_005609, NM_001164716, BC130514, BC126392,
Species
human
UniGene ID
Hs.154084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.