human PTPRF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTPRF.
shADV-220343
Ad-h-PTPRF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTPRF (protein tyrosine phosphatase, receptor type F). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BNAH2; LAR
Description (Vector)
PTPRF is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Gene ID
5792
Gene Name (Vector)
protein tyrosine phosphatase, receptor type F
Gene Symbol
PTPRF
HGNC ID
HGNC:9670
ORF Size (aa)
5697
ORF Size (bp)
5697 bp
RefSeq ID
NM_002840
RefSeq Synonyms
NM_130440, NM_002840, NM_001329140, NM_001329139, NM_001329138, NM_001329137, BC048768,
Species
human
UniGene ID
Hs.272062
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.