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human PTP4A1 shRNA silencing Adenovirus

Name 
Ad-h-PTP4A1-shRNA
Cat No 
shADV-220296
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PTP4A1.

shADV-220296
Ad-h-PTP4A1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTP4A1 (protein tyrosine phosphatase type IVA, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1
Description (Vector)
PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
Gene ID
7803
Gene Name (Vector)
protein tyrosine phosphatase type IVA, member 1
Gene Symbol
PTP4A1
HGNC ID
HGNC:9634
ORF Size (aa)
522
RefSeq ID
NM_003463
RefSeq Synonyms
NM_003463, BC045571, BC023975,
Species
human
UniGene ID
Hs.227777

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.