human PTGER4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTGER4.
shADV-220242
Ad-h-PTGER4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTGER4 (prostaglandin E receptor 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EP4; EP4R
Description (Vector)
PTGER4 is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.
Gene ID
5734
Gene Name (Vector)
prostaglandin E receptor 4
Gene Symbol
PTGER4
HGNC ID
HGNC:9596
ORF Size (aa)
1467
ORF Size (bp)
1467 bp
RefSeq ID
NM_000958
RefSeq Synonyms
NM_000958, BC113523, BC101534,
Species
human
UniGene ID
Hs.199248
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.