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human PROS1 shRNA silencing Adenovirus

Name 
Ad-h-PROS1-shRNA
Cat No 
shADV-219940
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human PROS1.

shADV-219940
Ad-h-PROS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PROS1 (protein S (alpha)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PROS; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
Description (Vector)
PROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.
Gene ID
5627
Gene Name (Vector)
protein S (alpha)
Gene Symbol
PROS1
HGNC ID
HGNC:9456
ORF Size (aa)
2031
ORF Size (bp)
2031 bp
RefSeq ID
NM_000313
RefSeq Synonyms
NM_001314077, NM_000313, BC015801,
Species
human
UniGene ID
Hs.64016

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.