human PROC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PROC.
shADV-219921
Ad-h-PROC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PROC (protein C, inactivator of coagulation factors Va and VIIIa). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APC; PC; PROC1; THPH3; THPH4
Description (Vector)
PROC encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
Gene ID
5624
Gene Name (Vector)
protein C, inactivator of coagulation factors Va and VIIIa
Gene Symbol
PROC
HGNC ID
HGNC:9451
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_000312
RefSeq Synonyms
NM_000312, BC034377,
Species
human
UniGene ID
Hs.224698
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.