human PRMT5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRMT5.
shADV-219904
Ad-h-PRMT5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRMT5 (protein arginine methyltransferase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
72 kDa ICln-binding protein; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; IBP72; jak-binding protein 1; JBP1; protein arginine N-methyltransferase 5; shk1 kinase-binding protein 1 homolog; SKB1; SKB1 homolog; SKB1Hs
Description (eCommerce)
Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.
Gene ID
10419
Gene Name (eCommerce)
protein arginine methyltransferase 5
Gene Name (Vector)
protein arginine methyltransferase 5
Gene Symbol
PRMT5
HGNC ID
HGNC:10894
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1914
ORF Size (bp)
1914 bp
Protein Name (eCommerce)
Protein arginine N-methyltransferase 5
RefSeq ID
NM_006109
RefSeq Synonyms
NM_006109, NM_001282956, NM_001282955, NM_001282954, NM_001282953, NM_001039619, BC025979,
Research Areas
Cell Cycle,Chromatin Remodeling,Gene Expression,Histone Modification,Methyltransferase,Neurobiology,p53 Signaling,RNA Processing,RNA Transport,Signal Transduction,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,neurobiology,signal_transduction
Species
human
Target Sentence
Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.
UniGene ID
Hs.367854
UniProt ID (eCommerce)
O14744
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.