human PRKCE shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRKCE.
shADV-219862
Ad-h-PRKCE-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRKCE (protein kinase C epsilon). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
nPKC-epsilon; PKCE
Description (Vector)
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
Gene ID
5581
Gene Name (Vector)
protein kinase C epsilon
Gene Symbol
PRKCE
HGNC ID
HGNC:9401
ORF Size (aa)
2214
ORF Size (bp)
2214 bp
RefSeq ID
NM_005400
RefSeq Synonyms
NM_005400, BC109034, BC109033,
Species
human
UniGene ID
Hs.580351
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.