human PRKAG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRKAG1.
shADV-219845
Ad-h-PRKAG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AMPKG
Description (Vector)
PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene ID
5571
Gene Name (Vector)
protein kinase AMP-activated non-catalytic subunit gamma 1
Gene Symbol
PRKAG1
HGNC ID
HGNC:9385
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_002733
RefSeq Synonyms
NM_002733, NM_001206710, NM_001206709, BC000358,
Species
human
UniGene ID
Hs.530862
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.