human PPP1R16B shRNA silencing Adenovirus

Name
Ad-h-PPP1R16B-shRNA

Cat No
shADV-219625

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PPP1R16B.

shADV-219625

Ad-h-PPP1R16B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP1R16B (protein phosphatase 1 regulatory subunit 16B). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ANKRD4; TIMAP

Description (Vector)

PPP1R16B is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Gene ID

26051

Gene Name (Vector)

protein phosphatase 1 regulatory subunit 16B

Gene Symbol

PPP1R16B

HGNC ID

HGNC:15850

ORF Size (aa)

1704

ORF Size (bp)

1704 bp

RefSeq ID

NM_015568

RefSeq Synonyms

NM_015568, NM_001172735, BC152467, BC131801,

Species

human

UniGene ID

Hs.45719

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.