human POU2F1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POU2F1.
shADV-219471
Ad-h-POU2F1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POU2F1 (POU class 2 homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NF-A1; OCT1; oct-1; oct-1B; octamer-binding protein 1; octamer-binding transcription factor 1; Octamer-binding transcription factor-1; OTF1; OTF-1; POU class 2 homeobox 1 isoform Oct-1R; POU domain, class 2, transcription factor 1
Description (eCommerce)
OCT1 is a transcription factor that binds the octamer motif 5’-ATTTGCAT-3’ in promoters of various genes. OCT1 contains one homeobox DNA binding domain and is part of the POU transcription factor family due to the presence of one POU domain, a highly charged motif that selectively binds the octamer motif.
Description (Vector)
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 (PubMed 8314572)). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.(supplied by OMIM, Jul 2010)
Gene ID
5451
Gene Name (eCommerce)
POU class 2 homeobox 1
Gene Name (Vector)
POU class 2 homeobox 1
Gene Symbol
POU2F1
HGNC ID
HGNC:9212
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2232
ORF Size (bp)
2232 bp
Protein Name (eCommerce)
POU domain, class 2, transcription factor 1
RefSeq ID
NM_002697
RefSeq Synonyms
NM_002697, NM_001198786, NM_001198783, BC052274, BC003571, BC001664,
Research Areas
Gene Expression,Immunology,Neurobiology,T-cell Receptor Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
OCT1 is a transcription factor that binds the octamer motif 5’-ATTTGCAT-3’ in promoters of various genes. OCT1 contains one homeobox DNA binding domain and is part of the POU transcription factor family due to the presence of one POU domain, a highly charged motif that selectively binds the octamer motif.
UniGene ID
Hs.493649
UniProt ID (eCommerce)
P14859
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.