human POLD4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POLD4.
shADV-219350
Ad-h-POLD4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POLD4 (DNA polymerase delta 4, accessory subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p12; POLDS
Description (Vector)
POLD4 encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
57804
Gene Name (Vector)
DNA polymerase delta 4, accessory subunit
Gene Symbol
POLD4
HGNC ID
HGNC:14106
ORF Size (aa)
324
RefSeq ID
NM_021173
RefSeq Synonyms
NM_021173, NM_001256870, BC070250, BC001334,
Species
human
UniGene ID
Hs.523829
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.