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human PNMA3 shRNA silencing Adenovirus

Name 
Ad-h-PNMA3-shRNA
Cat No 
shADV-219298
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PNMA3.

shADV-219298
Ad-h-PNMA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PNMA3 (paraneoplastic Ma antigen 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MA3; MA5
Description (Vector)
PNMA3 is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
Gene ID
29944
Gene Name (Vector)
paraneoplastic Ma antigen 3
Gene Symbol
PNMA3
HGNC ID
HGNC:18742
ORF Size (aa)
1392
ORF Size (bp)
1392 bp
RefSeq ID
NM_013364
RefSeq Synonyms
NM_013364, NM_001282535, BC105098, BC105096,
Species
human
UniGene ID
Hs.449627

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.