human PLEKHG4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PLEKHG4.
shADV-219183
Ad-h-PLEKHG4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PLEKHG4 (pleckstrin homology and RhoGEF domain containing G4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHGEF44; PRTPHN1; SCA4
Description (Vector)
PLEKHG4 contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene.
Gene ID
25894
Gene Name (Vector)
pleckstrin homology and RhoGEF domain containing G4
Gene Symbol
PLEKHG4
HGNC ID
HGNC:24501
ORF Size (aa)
3456
ORF Size (bp)
3456 bp
RefSeq ID
NM_015432
RefSeq Synonyms
NM_015432, NM_001129731, NM_001129729, NM_001129728, NM_001129727, BC082974, BC063501, BC054486,
Species
human
UniGene ID
Hs.188781
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.