human LRAT Over-expression AAV

Name 
AAV-h-LRAT
Cat No 
AAV-214468
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LRAT.

AAV-214468
AAV-h-LRAT

Ready-to-use AAV expressing Human LRAT (lecithin retinol acyltransferase (phosphatidylcholine–retinol O-acyltransferase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LCA14
Description (Vector)
LRAT is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy.
Gene ID
9227
Gene Name (Vector)
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Gene Symbol
LRAT
HGNC ID
HGNC:6685
ORF Size (aa)
693
RefSeq ID
NM_004744
RefSeq Synonyms
NM_004744, NM_001301645, BC031053,
Species
human
UniGene ID
Hs.658427

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.