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human PLA2G5 shRNA silencing Adenovirus

Name 
Ad-h-PLA2G5-shRNA
Cat No 
shADV-219078
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PLA2G5.

shADV-219078
Ad-h-PLA2G5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PLA2G5 (phospholipase A2 group V). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FRFB; GV-PLA2; hVPLA(2); PLA2-10
Description (Vector)
PLA2G5 is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.
Gene ID
5322
Gene Name (Vector)
phospholipase A2 group V
Gene Symbol
PLA2G5
HGNC ID
HGNC:9038
ORF Size (aa)
417
RefSeq ID
NM_000929
RefSeq Synonyms
NM_000929, BC036792,
Species
human
UniGene ID
Hs.319438

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.