human PLA2G2A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PLA2G2A.
shADV-219065
Ad-h-PLA2G2A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PLA2G2A (phospholipase A2 group IIA). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
Description (Vector)
PLA2G2A is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
Gene ID
5320
Gene Name (Vector)
phospholipase A2 group IIA
Gene Symbol
PLA2G2A
HGNC ID
HGNC:9031
ORF Size (aa)
435
RefSeq ID
NM_000300
RefSeq Synonyms
NM_001161729, NM_001161728, NM_001161727, NM_000300, BC005919,
Species
human
UniGene ID
Hs.466804
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.