human PITX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PITX1.
shADV-219005
Ad-h-PITX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PITX1 (paired like homeodomain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BFT; CCF; hindlimb expressed homeobox protein backfoot; Hindlimb-expressed homeobox protein backfoot; homeobox protein PITX1; LBNBG; paired-like homeodomain transcription factor 1; pituitary homeo box 1; pituitary homeobox 1; pituitary otx-related factor; POTX; PTX1
Description (eCommerce)
PITX1 is a homeobox-containing transcription factor involved in the development of many organs. PITX1 has been demonstrated to play a critical role in pituitary organogenesis and can stimulate transcription from most pituitary hormone promoters. PITX1 has also been shown to stimulate the leutinizing hormone (LH)-beta gene promoter and may serve an important role in reproductive gene expression.
Description (Vector)
PITX1 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
Gene ID
5307
Gene Name (eCommerce)
paired like homeodomain 1
Gene Name (Vector)
paired like homeodomain 1
Gene Symbol
PITX1
HGNC ID
HGNC:9004
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
945
ORF Size (bp)
945 bp
Protein Name (eCommerce)
Pituitary homeobox 1
RefSeq ID
NM_002653
RefSeq Synonyms
NM_002653, BC009412, BC003685,
Research Areas
Cancer,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,transcription_translation
Species
human
Target Sentence
PITX1 is a homeobox-containing transcription factor involved in the development of many organs. PITX1 has been demonstrated to play a critical role in pituitary organogenesis and can stimulate transcription from most pituitary hormone promoters. PITX1 has also been shown to stimulate the leutinizing hormone (LH)-beta gene promoter and may serve an important role in reproductive gene expression.
UniGene ID
Hs.84136
UniProt ID (eCommerce)
P78337
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.