human PIK3R2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PIK3R2.
shADV-218957
Ad-h-PIK3R2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MPPH; MPPH1; p85; P85B; p85-BETA; phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3K regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
Description (eCommerce)
Phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2) binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00459].
Gene ID
5296
Gene Name (eCommerce)
phosphoinositide-3-kinase regulatory subunit 2
Gene Name (Vector)
phosphoinositide-3-kinase regulatory subunit 2
Gene Symbol
PIK3R2
HGNC ID
HGNC:8980
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2187
ORF Size (bp)
2187 bp
Protein Name (eCommerce)
Phosphatidylinositol 3-kinase regulatory subunit beta
RefSeq ID
NM_005027
RefSeq Synonyms
NM_005027, BC090249, BC070082, BC032647, BC014170,
Research Areas
Apoptosis,B-cell Receptor Signaling,BDNF Signaling,Breast Cancer,Cancer,Cardiac Hypertrophy,Cardiology,Cardiovascular,Colorectal Cancer,Cytokine Signaling,Cytoskeleton,EGFR Signaling,EGFR Signaling in Cancer,EPO Signaling,Estrogen Signaling,Fc Receptor Signaling,FGF Signaling,Glioma,GPCR Signaling,HIF-1 Signaling,Host-Virus Interactions,IFN Signaling,IGF-1 Signaling,Immunology,Innate Immunity,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,Kidney Cancer,Kinase/Phosphatase,Leptin Signaling,Leukemia,Lung Cancer,Metabolism/Metabolic Process,MicroRNAs in Cancer,mTOR Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,Notch Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,Prolactin Signaling,Prostate Cancer,RANKL-RANK Signaling,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,TNF Signaling,Toll-like Receptor Signaling,TSH Signaling,VEGF Signaling,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,genetics,immunology,infectious_disease,metabolism,neurobiology,signal_transduction,stem_cell_biology
Species
human
Target Sentence
Phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2) binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00459].
UniGene ID
Hs.371344
UniProt ID (eCommerce)
O00459
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.