human PIBF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PIBF1.
shADV-218894
Ad-h-PIBF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PIBF1 (progesterone immunomodulatory binding factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C13orf24; centrosomal protein of 90 kDa; CEP90; JBTS33; PIBF; progesterone-induced-blocking factor 1
Description (eCommerce)
Progesterone-induced blocking factor (PIBF) was originally discovered as a progesterone-induced protein that mediates the immunological effects of progesterone. PIBF is produced in PR-positive lymphocytes in healthy pregnant woman. A decreased percentage of PIBF-positive lymphocytes in pregnant woman is associated with premature pregnancy termination. PIBF appears to exert its immunomodulatory and anti-abortive effects by altering cytokine production and regulating natural killer (NK) cell activity.
Gene ID
10464
Gene Name (eCommerce)
progesterone immunomodulatory binding factor 1
Gene Name (Vector)
progesterone immunomodulatory binding factor 1
Gene Symbol
PIBF1
HGNC ID
HGNC:23352
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2097
ORF Size (bp)
2097 bp
Protein Name (eCommerce)
Progesterone-induced-blocking factor 1
RefSeq ID
NM_006346
RefSeq Synonyms
NM_006346, BC051911, BC041806,
Research Areas
Cell Biology,Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Progesterone-induced blocking factor (PIBF) was originally discovered as a progesterone-induced protein that mediates the immunological effects of progesterone. PIBF is produced in PR-positive lymphocytes in healthy pregnant woman. A decreased percentage of PIBF-positive lymphocytes in pregnant woman is associated with premature pregnancy termination. PIBF appears to exert its immunomodulatory and anti-abortive effects by altering cytokine production and regulating natural killer (NK) cell activity.
UniGene ID
Hs.441926
UniProt ID (eCommerce)
Q8WXW3
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.