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human PGBD1 shRNA silencing Adenovirus

Name 
Ad-h-PGBD1-shRNA
Cat No 
shADV-218724
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PGBD1.

shADV-218724
Ad-h-PGBD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PGBD1 (piggyBac transposable element derived 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cerebral protein 4; dJ874C20.4; HUCEP-4; piggyBac transposable element-derived protein 1; SCAND4
Description (eCommerce)
PiggyBac transposable element derived 1 (PGBD1) is a member of the subfamily of piggyBac transposable element derived (PGBD) genes. The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. PGDB1 has been implicated as a candidate gene for risk of alzhimer’s and schizophrenia.
Description (Vector)
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
84547
Gene Name (eCommerce)
piggyBac transposable element derived 1
Gene Name (Vector)
piggyBac transposable element derived 1
Gene Symbol
PGBD1
HGNC ID
HGNC:19398
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2430
ORF Size (bp)
2430 bp
Protein Name (eCommerce)
PiggyBac transposable element-derived protein 1
RefSeq ID
NM_032507
RefSeq Synonyms
NM_032507, NM_001184743, BC128585,
Research Areas
Host-Virus Interactions,Neurobiology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,infectious_disease,neurobiology,transcription_translation
Species
human
Target Sentence
PiggyBac transposable element derived 1 (PGBD1) is a member of the subfamily of piggyBac transposable element derived (PGBD) genes. The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. PGDB1 has been implicated as a candidate gene for risk of alzhimer’s and schizophrenia.
UniGene ID
Hs.144527
UniProt ID (eCommerce)
Q96JS3

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.