human PEA15 shRNA silencing Adenovirus

Name 
Ad-h-PEA15-shRNA
Cat No 
shADV-218586
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PEA15.

shADV-218586
Ad-h-PEA15-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PEA15 (phosphoprotein enriched in astrocytes 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED
Description (Vector)
PEA15 encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.
Gene ID
8682
Gene Name (Vector)
phosphoprotein enriched in astrocytes 15
Gene Symbol
PEA15
HGNC ID
HGNC:8822
ORF Size (aa)
393
RefSeq ID
NM_003768
RefSeq Synonyms
NM_003768, NM_001297578, NM_001297577, NM_001297576, BC022554, BC010469, BC002426,
Species
human
UniGene ID
Hs.517216

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.