human PDZD2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDZD2.
shADV-218572
Ad-h-PDZD2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDZD2 (PDZ domain containing 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIPC; PAPIN; PDZK3; PIN1
Description (Vector)
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Gene ID
23037
Gene Name (Vector)
PDZ domain containing 2
Gene Symbol
PDZD2
HGNC ID
HGNC:18486
ORF Size (aa)
8520
ORF Size (bp)
8520 bp
RefSeq ID
NM_178140
RefSeq Synonyms
NM_178140, BC172231,
Species
human
UniGene ID
Hs.481819
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.