human PDYN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PDYN.
shADV-218570
Ad-h-PDYN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PDYN (prodynorphin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADCA; PENKB; SCA23
Description (Vector)
PDYN is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
5173
Gene Name (Vector)
prodynorphin
Gene Symbol
PDYN
HGNC ID
HGNC:8820
ORF Size (aa)
765
RefSeq ID
NM_024411
RefSeq Synonyms
NM_024411, NM_001190900, NM_001190899, NM_001190898, NM_001190892, BC026334,
Species
human
UniGene ID
Hs.22584
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.